Read the paragraph below and choose the alternative that fills in correctly and respectively the blanks below.

“Ketamine, is also a drug used recreationally to achieve a sort “out of body” high, “is not all ready for prime time”, said Dr. James Murrough, an associate professor of psychiatry at Icahn School of Medicine at Mt. Sinai. But it is approved use in anesthesia, so it’s available legally. And years of small and preliminary trials have offered tantalizing evidence of its powerful and fast-acting antidepressant effect patients whose depression has failed to yield to other treatments.”

Ketamine: a potential rescue drug for depression takes a step forward. Available in: http://www.latimes.com